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Nuclear importin α and its physiological importance

Importin α is recognized as a classical nuclear localization signal (cNLS) receptor which mediates nucleocytoplasmic transport. However, it rapidly accumulates in the nucleus in response to cellular stresses, including oxidative stress, causing a blockade of the classical nuclear import pathway. We...

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Detalles Bibliográficos
Autores principales: Miyamoto, Yoichi, Loveland, Kate L., Yoneda, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376070/
https://www.ncbi.nlm.nih.gov/pubmed/22808339
http://dx.doi.org/10.4161/cib.19194