Cargando…
Nuclear importin α and its physiological importance
Importin α is recognized as a classical nuclear localization signal (cNLS) receptor which mediates nucleocytoplasmic transport. However, it rapidly accumulates in the nucleus in response to cellular stresses, including oxidative stress, causing a blockade of the classical nuclear import pathway. We...
Autores principales: | Miyamoto, Yoichi, Loveland, Kate L., Yoneda, Yoshihiro |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376070/ https://www.ncbi.nlm.nih.gov/pubmed/22808339 http://dx.doi.org/10.4161/cib.19194 |
Ejemplares similares
-
Cellular stresses induce the nuclear accumulation of importin α and cause a conventional nuclear import block
por: Miyamoto, Yoichi, et al.
Publicado: (2004) -
Importin α: functions as a nuclear transport factor and beyond
por: OKA, Masahiro, et al.
Publicado: (2018) -
Specific interaction with the nuclear transporter importin α2 can modulate paraspeckle protein 1 delivery to nuclear paraspeckles
por: Major, Andrew T., et al.
Publicado: (2015) -
Development of a pipeline for automated, high-throughput analysis of paraspeckle proteins reveals specific roles for importin α proteins
por: Major, Andrew T., et al.
Publicado: (2017) -
Importin α3 (KPNA3) Deficiency Augments Effortful Reward-Seeking Behavior in Mice
por: Aomine, Yoshiatsu, et al.
Publicado: (2022)