The hTERT Promoter Enhances the Antitumor Activity of an Oncolytic Adenovirus under a Hypoxic Microenvironment

Hypoxia is a microenvironmental factor that contributes to the invasion, progression and metastasis of tumor cells. Hypoxic tumor cells often show more resistance to conventional chemoradiotherapy than normoxic tumor cells, suggesting the requirement of novel antitumor therapies to efficiently elimi...

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Detalles Bibliográficos
Autores principales: Hashimoto, Yuuri, Tazawa, Hiroshi, Teraishi, Fuminori, Kojima, Toru, Watanabe, Yuichi, Uno, Futoshi, Yano, Shuya, Urata, Yasuo, Kagawa, Shunsuke, Fujiwara, Toshiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376103/
https://www.ncbi.nlm.nih.gov/pubmed/22720091
http://dx.doi.org/10.1371/journal.pone.0039292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376103/
https://www.ncbi.nlm.nih.gov/pubmed/22720091
http://dx.doi.org/10.1371/journal.pone.0039292

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