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Prenatal Arsenic Exposure Alters Gene Expression in the Adult Liver to a Proinflammatory State Contributing to Accelerated Atherosclerosis

The mechanisms by which environmental toxicants alter developmental processes predisposing individuals to adult onset chronic disease are not well-understood. Transplacental arsenic exposure promotes atherogenesis in apolipoprotein E-knockout (ApoE(−/−)) mice. Because the liver plays a central role...

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Detalles Bibliográficos
Autores principales: States, J. Christopher, Singh, Amar V., Knudsen, Thomas B., Rouchka, Eric C., Ngalame, Ntube O., Arteel, Gavin E., Piao, Yulan, Ko, Minoru S. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376138/
https://www.ncbi.nlm.nih.gov/pubmed/22719926
http://dx.doi.org/10.1371/journal.pone.0038713