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DNA Fragmentation Simulation Method (FSM) and Fragment Size Matching Improve aCGH Performance of FFPE Tissues

Whole-genome copy number analysis platforms, such as array comparative genomic hybridization (aCGH) and single nucleotide polymorphism (SNP) arrays, are transformative research discovery tools. In cancer, the identification of genomic aberrations with these approaches has generated important diagnos...

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Detalles Bibliográficos
Autores principales: Craig, Justin M., Vena, Natalie, Ramkissoon, Shakti, Idbaih, Ahmed, Fouse, Shaun D., Ozek, Memet, Sav, Aydin, Hill, D. Ashley, Margraf, Linda R., Eberhart, Charles G., Kieran, Mark W., Norden, Andrew D., Wen, Patrick Y., Loda, Massimo, Santagata, Sandro, Ligon, Keith L., Ligon, Azra H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376148/
https://www.ncbi.nlm.nih.gov/pubmed/22719973
http://dx.doi.org/10.1371/journal.pone.0038881