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Deletion of the epidermal growth factor receptor in renal proximal tubule epithelial cells delays recovery from acute kidney injury
To determine the role of epidermal growth factor receptor (EGFR) activation in renal functional and structural recovery from acute kidney injury (AKI), we generated mice with a specific EGFR deletion in the renal proximal tubule (EGFR(ptKO)). Ischemia–reperfusion injury markedly activated EGFR in co...
Autores principales: | Chen, Jianchun, Chen, Jian-Kang, Harris, Raymond C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376190/ https://www.ncbi.nlm.nih.gov/pubmed/22418982 http://dx.doi.org/10.1038/ki.2012.43 |
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