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Contributions of Intracellular Ions to Kv Channel Voltage Sensor Dynamics

Voltage-sensing domains (VSDs) of Kv channels control ionic conductance through coupling of the movement of charged residues in the S4 segment to conformational changes at the cytoplasmic region of the pore domain, that allow K(+) ions to flow. Conformational transitions within the VSD are induced b...

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Detalles Bibliográficos
Autores principales: Goodchild, Samuel J., Fedida, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376422/
https://www.ncbi.nlm.nih.gov/pubmed/22719727
http://dx.doi.org/10.3389/fphar.2012.00114