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Gene Set Enrichment Analysis Identifies LIF as a Negative Regulator of Human Th2 Cell Differentiation

In this study we show that IL-4 is crucial during reinforcement window of human Th2 differentiation for optimal Th2 development. We have also shown here that during this stage, IL-4 helps in cellular decision-making process of differentiation versus proliferation. We have combined computational and...

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Detalles Bibliográficos
Autores principales: Ullah, Ubaid, Tripathi, Parul, Lahesmaa, Riitta, Rao, Kanury V. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376453/
https://www.ncbi.nlm.nih.gov/pubmed/22712053
http://dx.doi.org/10.1038/srep00464