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Boosting regulatory T cell function by CD4 stimulation enters the clinic

Understanding tolerance mechanisms at the cellular and molecular level holds the promise to establish novel immune intervention therapies in patients with allergy or autoimmunity and to prevent transplant rejection. Administration of mAb against the CD4 molecule has been found to be exceptionally we...

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Detalles Bibliográficos
Autores principales: Becker, Christian, Bopp, Tobias, Jonuleit, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376463/
https://www.ncbi.nlm.nih.gov/pubmed/22719741
http://dx.doi.org/10.3389/fimmu.2012.00164