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A Pro-Drug Approach for Selective Modulation of AI-2-Mediated Bacterial Cell-to-Cell Communication

The universal quorum sensing autoinducer, AI-2, is utilized by several bacteria. Analogs of AI-2 have the potential to modulate bacterial behavior. Selectively quenching the communication of a few bacteria, in the presence of several others in an ecosystem, using analogs of AI-2 is non-trivial due t...

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Detalles Bibliográficos
Autores principales: Guo, Min, Gamby, Sonja, Nakayama, Shizuka, Smith, Jacqueline, Sintim, Herman O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376627/
https://www.ncbi.nlm.nih.gov/pubmed/22737036
http://dx.doi.org/10.3390/s120303762