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Eps15R is required for bone morphogenetic protein signalling and differentially compartmentalizes with Smad proteins

Transforming growth factor β superfamily members signal through Smad transcription factors. Bone morphogenetic proteins (BMPs) act via Smads 1, 5 and 8 and TGF-βs signal through Smads 2 and 3. The endocytic adaptor protein Eps15R, or ‘epidermal growth factor (EGF) receptor pathway substrate 15-relat...

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Detalles Bibliográficos
Autores principales: Callery, Elizabeth M., Park, Chong Yon, Xu, Xin, Zhu, Haitao, Smith, James C., Thomsen, Gerald H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376731/
https://www.ncbi.nlm.nih.gov/pubmed/22724065
http://dx.doi.org/10.1098/rsob.120060