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Acquiring Metastatic Competence by Oral Squamous Cell Carcinoma Cells Is Associated with Differential Expression of α-Tubulin Isoforms

We performed comparative global proteomics analyses of patient-matched primary (686Tu) and metastatic (686Ln) OSCC cells. The metastatic OSCC 686Ln cells showed greater in vitro migratory/invasive potential and distinct cell shape from their parental primary 686Tu cells. Ettan DIGE analysis revealed...

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Detalles Bibliográficos
Autores principales: Lou, Becky, Engler, David, Dubinsky, William, Wu, Jean, Vigneswaran, Nadarajah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376782/
https://www.ncbi.nlm.nih.gov/pubmed/22719762
http://dx.doi.org/10.1155/2012/491685