Reconstruction of nuclear receptor network reveals that NR2E3 is a novel upstream regulator of ESR1 in breast cancer

ESR1 is one of the most important transcription factors and therapeutic targets in breast cancer. By applying systems-level re-analysis of publicly available gene expression data, we uncovered a potential regulator of ESR1. We demonstrated that orphan nuclear receptor NR2E3 regulates ESR1 via direct...

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Detalles Bibliográficos
Autores principales: Park, Yun-Yong, Kim, Kyounghyun, Kim, Sang-Bae, Hennessy, Bryan T, Kim, Soo Mi, Park, Eun Sung, Lim, Jae Yun, Li, Jane, Lu, Yiling, Gonzalez-Angulo, Ana Maria, Jeong, Woojin, Mills, Gordon B, Safe, Stephen, Lee, Ju-Seog
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376834/
https://www.ncbi.nlm.nih.gov/pubmed/22174013
http://dx.doi.org/10.1002/emmm.201100187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376834/
https://www.ncbi.nlm.nih.gov/pubmed/22174013
http://dx.doi.org/10.1002/emmm.201100187

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