Detection of Microregional Hypoxia in Mouse Cerebral Cortex by Two-photon Imaging of Endogenous NADH Fluorescence

The brain's ability to function at high levels of metabolic demand depends on continuous oxygen supply through blood flow and tissue oxygen diffusion. Here we present a visualized experimental and methodological protocol to directly visualize microregional tissue hypoxia and to infer perivascul...

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Detalles Bibliográficos
Autores principales: Polesskaya, Oksana, Sun, Anita, Salahura, Gheorghe, Silva, Jharon N., Dewhurst, Stephen, Kasischke, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2012
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376929/
https://www.ncbi.nlm.nih.gov/pubmed/22370971
http://dx.doi.org/10.3791/3466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376929/
https://www.ncbi.nlm.nih.gov/pubmed/22370971
http://dx.doi.org/10.3791/3466

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