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Reconstruction of Exposure to m-Xylene from Human Biomonitoring Data Using PBPK Modelling, Bayesian Inference, and Markov Chain Monte Carlo Simulation

There are numerous biomonitoring programs, both recent and ongoing, to evaluate environmental exposure of humans to chemicals. Due to the lack of exposure and kinetic data, the correlation of biomarker levels with exposure concentrations leads to difficulty in utilizing biomonitoring data for biolog...

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Detalles Bibliográficos
Autores principales: McNally, Kevin, Cotton, Richard, Cocker, John, Jones, Kate, Bartels, Mike, Rick, David, Price, Paul, Loizou, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376947/
https://www.ncbi.nlm.nih.gov/pubmed/22719759
http://dx.doi.org/10.1155/2012/760281