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Reconstruction of Exposure to m-Xylene from Human Biomonitoring Data Using PBPK Modelling, Bayesian Inference, and Markov Chain Monte Carlo Simulation
There are numerous biomonitoring programs, both recent and ongoing, to evaluate environmental exposure of humans to chemicals. Due to the lack of exposure and kinetic data, the correlation of biomarker levels with exposure concentrations leads to difficulty in utilizing biomonitoring data for biolog...
Autores principales: | McNally, Kevin, Cotton, Richard, Cocker, John, Jones, Kate, Bartels, Mike, Rick, David, Price, Paul, Loizou, George |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376947/ https://www.ncbi.nlm.nih.gov/pubmed/22719759 http://dx.doi.org/10.1155/2012/760281 |
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