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Systemic cancer immunotherapy with Toll-like receptor 7 agonists: Timing is everything

Toll-like receptor (TLR) 7 agonists represent a promising strategy for the immunotherapy of cancer. We have recently investigated the influence of TLR tolerance on the efficacy of systemic tumor treatment with TLR7 ligands. We propose that considering the kinetics of receptor sensitivity highly impr...

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Detalles Bibliográficos
Autores principales: Hotz, Christian, Bourquin, Carole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376978/
https://www.ncbi.nlm.nih.gov/pubmed/22720251
http://dx.doi.org/10.4161/onci.1.2.18169