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Regulatory T cells in the bone marrow microenvironment in patients with prostate cancer

Human prostate cancer frequently metastasizes to bone marrow. What defines the cellular and molecular predilection for prostate cancer to metastasize to bone marrow is not well understood. CD4(+)CD25(+) regulatory T (Treg) cells contribute to self-tolerance and tumor immune pathology. We now show th...

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Detalles Bibliográficos
Autores principales: Zhao, Ende, Wang, Lin, Dai, Jinlu, Kryczek, Ilona, Wei, Shuang, Vatan, Linda, Altuwaijri, Saleh, Sparwasser, Tim, Wang, Guobin, Keller, Evan T., Zou, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376984/
https://www.ncbi.nlm.nih.gov/pubmed/22720236
http://dx.doi.org/10.4161/onci.1.2.18480