Cargando…

T cells and T cell tumors efficiently generate antigen-specific cytotoxic T cell immunity when modified with an NKT ligand

Various Invariant NKT (iNKT) cell ligands have been shown as potent adjuvants in boosting T cell reactivates to antigens on professional APC. Non-professional APC, such as T cells, also co-expressing MHC class I and CD1d, have been unattractive cell vaccine carriers due to their poor immunogenicity....

Descripción completa

Detalles Bibliográficos
Autores principales: Chung, Yeonseok, Lee, Young-Hee, Zhang, Yongliang, Martin-Orozco, Natalia, Yamazaki, Tomohide, Zhou, Dapeng, Kang, Chang-Yuil, Hwu, Patrick, Kwak, Larry W., Dong, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376985/
https://www.ncbi.nlm.nih.gov/pubmed/22720235
http://dx.doi.org/10.4161/onci.1.2.18479