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IL-33/ST2 axis in innate and acquired immunity to tumors

Interleukin-33, a ligand for ST2/T1, has an important role in allergy, autoimmunity and inflammation. The role of IL-33/ST2 axis in cancer is not elucidated. Using metastatic breast cancer model we provide evidence that lack of ST2 signaling led to reduced tumor growth and metastasis and enhanced an...

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Detalles Bibliográficos
Autores principales: Jovanovic, Ivan P., Pejnovic, Nada N., Radosavljevic, Gordana D., Arsenijevic, Nebojsa N., Lukic, Miodrag L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376988/
https://www.ncbi.nlm.nih.gov/pubmed/22720252
http://dx.doi.org/10.4161/onci.1.2.18131