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The double-edge sword effect of anti-CD73 cancer therapy

We and others have identified CD73 as a new cancer target. I hereafter discuss that targeted blockade of CD73 has the effect of a “double-edge sword,” able on the one hand to rescue endogenous adaptive anti-tumor immune responses, and on the other hand, inhibit the metastatic potential of tumor cell...

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Detalles Bibliográficos
Autor principal: Stagg, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376997/
https://www.ncbi.nlm.nih.gov/pubmed/22720247
http://dx.doi.org/10.4161/onci.1.2.18101