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The double-edge sword effect of anti-CD73 cancer therapy
We and others have identified CD73 as a new cancer target. I hereafter discuss that targeted blockade of CD73 has the effect of a “double-edge sword,” able on the one hand to rescue endogenous adaptive anti-tumor immune responses, and on the other hand, inhibit the metastatic potential of tumor cell...
Autor principal: | Stagg, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376997/ https://www.ncbi.nlm.nih.gov/pubmed/22720247 http://dx.doi.org/10.4161/onci.1.2.18101 |
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