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Oxaliplatin-induced cold hypersensitivity is due to remodelling of ion channel expression in nociceptors

Cold hypersensitivity is the hallmark of oxaliplatin-induced neuropathy, which develops in nearly all patients under this chemotherapy. To date, pain management strategies have failed to alleviate these symptoms, hence development of adapted analgesics is needed. Here, we report that oxaliplatin exa...

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Detalles Bibliográficos
Autores principales: Descoeur, Juliette, Pereira, Vanessa, Pizzoccaro, Anne, Francois, Amaury, Ling, Bing, Maffre, Violette, Couette, Brigitte, Busserolles, Jérôme, Courteix, Christine, Noel, Jacques, Lazdunski, Michel, Eschalier, Alain, Authier, Nicolas, Bourinet, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377073/
https://www.ncbi.nlm.nih.gov/pubmed/21438154
http://dx.doi.org/10.1002/emmm.201100134