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The isoenzyme of glutaminyl cyclase is an important regulator of monocyte infiltration under inflammatory conditions

Acute and chronic inflammatory disorders are characterized by detrimental cytokine and chemokine expression. Frequently, the chemotactic activity of cytokines depends on a modified N-terminus of the polypeptide. Among those, the N-terminus of monocyte chemoattractant protein 1 (CCL2 and MCP-1) is mo...

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Detalles Bibliográficos
Autores principales: Cynis, Holger, Hoffmann, Torsten, Friedrich, Daniel, Kehlen, Astrid, Gans, Kathrin, Kleinschmidt, Martin, Rahfeld, Jens-Ulrich, Wolf, Raik, Wermann, Michael, Stephan, Anett, Haegele, Monique, Sedlmeier, Reinhard, Graubner, Sigrid, Jagla, Wolfgang, Müller, Anke, Eichentopf, Rico, Heiser, Ulrich, Seifert, Franziska, Quax, Paul H A, de Vries, Margreet R, Hesse, Isabel, Trautwein, Daniela, Wollert, Ulrich, Berg, Sabine, Freyse, Ernst-Joachim, Schilling, Stephan, Demuth, Hans-Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377097/
https://www.ncbi.nlm.nih.gov/pubmed/21774078
http://dx.doi.org/10.1002/emmm.201100158