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Medial prefrontal cortex serotonin 1A and 2A receptor binding interacts to predict threat-related amygdala reactivity

BACKGROUND: The amygdala and medial prefrontal cortex (mPFC) comprise a key corticolimbic circuit that helps shape individual differences in sensitivity to threat and the related risk for psychopathology. Although serotonin (5-HT) is known to be a key modulator of this circuit, the specific receptor...

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Detalles Bibliográficos
Autores principales: Fisher, Patrick M, Price, Julie C, Meltzer, Carolyn C, Moses-Kolko, Eydie L, Becker, Carl, Berga, Sarah L, Hariri, Ahmad R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377121/
https://www.ncbi.nlm.nih.gov/pubmed/22738071
http://dx.doi.org/10.1186/2045-5380-1-2