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HIV-1 replication activates CD4(+) T cells with specificities for persistent herpes viruses

Hyperactivation of CD4(+) T cells is a hallmark of untreated HIV-1 infection. The antigenic specificities of activated CD4(+) T cells and the underlying mechanisms leading to their activation remain thus far elusive. We report here that during HIV rebound the dynamics of HIV-specific CD4(+) T cells...

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Detalles Bibliográficos
Autores principales: Haas, Anna, Rehr, Manuela, Graw, Frederik, Rusert, Peter, Bossart, Walter, Kuster, Herbert, Trkola, Alexandra, Günthard, Huldrych F, Oxenius, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377320/
https://www.ncbi.nlm.nih.gov/pubmed/20533427
http://dx.doi.org/10.1002/emmm.201000075