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Déjà vu with a twist: transglutaminases in bioenergetics and transcriptional dysfunction in Huntington's disease

The article by McConoughey et al in the current issue of EMBO Molecular Medicine examines the contribution of transglutaminase 2 (TG2) to Huntington's disease (HD) pathogenesis. The authors find that TG2 inhibition can ameliorate HD neurodegeneration, and thereby elevate the status of transglut...

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Detalles Bibliográficos
Autores principales: Kazemi-Esfarjani, Parsa, La Spada, Albert R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377338/
https://www.ncbi.nlm.nih.gov/pubmed/20730854
http://dx.doi.org/10.1002/emmm.201000092