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Déjà vu with a twist: transglutaminases in bioenergetics and transcriptional dysfunction in Huntington's disease
The article by McConoughey et al in the current issue of EMBO Molecular Medicine examines the contribution of transglutaminase 2 (TG2) to Huntington's disease (HD) pathogenesis. The authors find that TG2 inhibition can ameliorate HD neurodegeneration, and thereby elevate the status of transglut...
Autores principales: | Kazemi-Esfarjani, Parsa, La Spada, Albert R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
WILEY-VCH Verlag
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377338/ https://www.ncbi.nlm.nih.gov/pubmed/20730854 http://dx.doi.org/10.1002/emmm.201000092 |
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