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Could successful (mitochondrial) networking help prevent Huntington's disease?

Polyglutamine expansions in huntingtin (Htt) are known to cause the profound neurodegenerative disorder, Huntington's disease (HD). Mitochondrial dysfunction has long been implicated in the pathophysiology of HD, but the underlying mechanism remains obscure. An article by Costa et al in this mo...

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Detalles Bibliográficos
Autores principales: Oliveira, Jorge M A, Lightowlers, Robert N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377349/
https://www.ncbi.nlm.nih.gov/pubmed/21117121
http://dx.doi.org/10.1002/emmm.201000104