An NR2B-Dependent Decrease in the Expression of trkB Receptors Precedes the Disappearance of Dopaminergic Cells in Substantia Nigra in a Rat Model of Presymptomatic Parkinson's Disease

Compensatory changes occurring during presymptomatic stages of Parkinson's disease (PD) would explain that the clinical symptoms of the disease appear late, when the degenerative process is quite advanced. Several data support the proposition that brain-derived neurotrophic factor (BDNF) could...

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Detalles Bibliográficos
Autores principales: Riquelme, Eduardo, Abarca, Jorge, Campusano, Jorge M., Bustos, Gonzalo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377358/
https://www.ncbi.nlm.nih.gov/pubmed/22720191
http://dx.doi.org/10.1155/2012/129605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377358/
https://www.ncbi.nlm.nih.gov/pubmed/22720191
http://dx.doi.org/10.1155/2012/129605

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