Intracellular Invasion of Orientia tsutsugamushi Activates Inflammasome in ASC-Dependent Manner

Orientia tsutsugamushi, a causative agent of scrub typhus, is an obligate intracellular bacterium, which escapes from the endo/phagosome and replicates in the host cytoplasm. O. tsutsugamushi infection induces production of pro-inflammatory mediators including interleukin-1β (IL-1β), which is secret...

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Detalles Bibliográficos
Autores principales: Koo, Jung-Eun, Hong, Hye-Jin, Dearth, Andrea, Kobayashi, Koichi S., Koh, Young-Sang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377614/
https://www.ncbi.nlm.nih.gov/pubmed/22723924
http://dx.doi.org/10.1371/journal.pone.0039042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377614/
https://www.ncbi.nlm.nih.gov/pubmed/22723924
http://dx.doi.org/10.1371/journal.pone.0039042

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