Genotype-Specific Differences between Mouse CNS Stem Cell Lines Expressing Frontotemporal Dementia Mutant or Wild Type Human Tau

Stem cell (SC) lines that capture the genetics of disease susceptibility provide new research tools. To assess the utility of mouse central nervous system (CNS) SC-containing neurosphere cultures for studying heritable neurodegenerative disease, we compared neurosphere cultures from transgenic mice...

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Detalles Bibliográficos
Autores principales: Orr, Miranda E., Pitstick, Rose, Canine, Brenda, Ashe, Karen H., Carlson, George A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377636/
https://www.ncbi.nlm.nih.gov/pubmed/22723997
http://dx.doi.org/10.1371/journal.pone.0039328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377636/
https://www.ncbi.nlm.nih.gov/pubmed/22723997
http://dx.doi.org/10.1371/journal.pone.0039328

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