Cargando…

Genotype-Specific Differences between Mouse CNS Stem Cell Lines Expressing Frontotemporal Dementia Mutant or Wild Type Human Tau

Stem cell (SC) lines that capture the genetics of disease susceptibility provide new research tools. To assess the utility of mouse central nervous system (CNS) SC-containing neurosphere cultures for studying heritable neurodegenerative disease, we compared neurosphere cultures from transgenic mice...

Descripción completa

Detalles Bibliográficos
Autores principales:	Orr, Miranda E., Pitstick, Rose, Canine, Brenda, Ashe, Karen H., Carlson, George A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377636/ https://www.ncbi.nlm.nih.gov/pubmed/22723997 http://dx.doi.org/10.1371/journal.pone.0039328

Ejemplares similares

Plasma tau is increased in frontotemporal dementia
por: Foiani, Martha S, et al.
Publicado: (2018)

Frontotemporal dementia mutant Tau promotes aberrant Fyn nanoclustering in hippocampal dendritic spines
por: Padmanabhan, Pranesh, et al.
Publicado: (2019)

Inhibition of Sirtuin 2 with Sulfobenzoic Acid Derivative AK1 is Non-Toxic and Potentially Neuroprotective in a Mouse Model of Frontotemporal Dementia
por: Spires-Jones, Tara L., et al.
Publicado: (2012)

Differential compartmental processing and phosphorylation of pathogenic human tau and native mouse tau in the line 66 model of frontotemporal dementia
por: Lemke, Nora, et al.
Publicado: (2021)

Proteomic Analysis of Hydromethylthionine in the Line 66 Model of Frontotemporal Dementia Demonstrates Actions on Tau-Dependent and Tau-Independent Networks
por: Schwab, Karima, et al.
Publicado: (2021)

Clinical value of neurofilament and phospho-tau/tau ratio in the frontotemporal dementia spectrum
por: Meeter, Lieke H.H., et al.
Publicado: (2018)

Distinct Neurodegenerative Changes in an Induced Pluripotent Stem Cell Model of Frontotemporal Dementia Linked to Mutant TAU Protein
por: Ehrlich, Marc, et al.
Publicado: (2015)

Astrocyte pathology in a human neural stem cell model of frontotemporal dementia caused by mutant TAU protein
por: Hallmann, Anna-Lena, et al.
Publicado: (2017)

(18)F-MK-6240 tau-PET in genetic frontotemporal dementia
por: Levy, Jake P, et al.
Publicado: (2021)

Frontotemporal Lobar Dementia Mutant Tau Impairs Axonal Transport through a Protein Phosphatase 1γ-Dependent Mechanism
por: Combs, Benjamin, et al.
Publicado: (2021)

Discriminative and prognostic potential of cerebrospinal fluid phosphoTau/tau ratio and neurofilaments for frontotemporal dementia subtypes
por: Pijnenburg, Yolande A.L., et al.
Publicado: (2015)

Frontotemporal dementia
por: Warren, Jason D, et al.
Publicado: (2013)

(18)F-flortaucipir (AV-1451) tau PET in frontotemporal dementia syndromes
por: Tsai, Richard M., et al.
Publicado: (2019)

Human Induced Pluripotent Stem Cell Models of Frontotemporal Dementia With Tau Pathology
por: Kühn, Rebekka, et al.
Publicado: (2021)

PERK inhibition prevents tau-mediated neurodegeneration in a mouse model of frontotemporal dementia
por: Radford, Helois, et al.
Publicado: (2015)

Frontotemporal Dementia-Associated N279K Tau Mutation Localizes at the Nuclear Compartment
por: Ritter, Maxi L., et al.
Publicado: (2018)

Microtubules Deform the Nuclear Membrane and Disrupt Nucleocytoplasmic Transport in Tau-Mediated Frontotemporal Dementia
por: Paonessa, Francesco, et al.
Publicado: (2019)

Searching for novel cerebrospinal fluid biomarkers of tau pathology in frontotemporal dementia: an elusive quest
por: Foiani, Martha S, et al.
Publicado: (2019)

Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models
por: Silva, M Catarina, et al.
Publicado: (2019)

Neuroimaging signatures of frontotemporal dementia genetics: C9ORF72, tau, progranulin and sporadics
por: Whitwell, Jennifer L., et al.
Publicado: (2012)

Young‐onset frontotemporal dementia in a homozygous tau R406W mutation carrier
por: Ng, Adeline S. L., et al.
Publicado: (2015)

Frontotemporal Dementias: A Review
por: Weder, Natalie D, et al.
Publicado: (2007)

Frontotemporal dementia to Alzheimer's disease
por: Silveri, Maria Caterina
Publicado: (2007)

Frontotemporal dementia: An updated overview
por: Mohandas, E., et al.
Publicado: (2009)

Music, reward and frontotemporal dementia
por: Fletcher, Phillip D., et al.
Publicado: (2014)

Mentalising music in frontotemporal dementia
por: Downey, Laura E., et al.
Publicado: (2013)

The Genetics of Monogenic Frontotemporal Dementia
por: Takada, Leonel T.
Publicado: (2015)

Precision Medicine for Frontotemporal Dementia
por: Liu, Mu-N, et al.
Publicado: (2019)

An update on genetic frontotemporal dementia
por: Greaves, Caroline V., et al.
Publicado: (2019)

Frontotemporal Dementia and Glucose Metabolism
por: Garrett, Liam Rodney, et al.
Publicado: (2022)

Phenocopy syndrome of frontotemporal dementia
por: Martins, D., et al.
Publicado: (2021)

Psychiatric Misdiagnosis in Frontotemporal Dementia
por: Yay Pençe, A., et al.
Publicado: (2022)

Advances in the Understanding of Frontotemporal Dementia
por: Bandopadhyay, Rina, et al.
Publicado: (2023)

Human iPSC-Derived Neuronal Model of Tau-A152T Frontotemporal Dementia Reveals Tau-Mediated Mechanisms of Neuronal Vulnerability
por: Silva, M. Catarina, et al.
Publicado: (2016)

Expression and purification of tau protein and its frontotemporal dementia variants using a cleavable histidine tag
por: Karikari, Thomas K., et al.
Publicado: (2017)

[(18)F]RO948 tau positron emission tomography in genetic and sporadic frontotemporal dementia syndromes
por: Santillo, Alexander F., et al.
Publicado: (2022)

Frontotemporal Dementia P301L Mutation Potentiates but Is Not Sufficient to Cause the Formation of Cytotoxic Fibrils of Tau
por: Wang, Kuang-Wei, et al.
Publicado: (2023)

Tau physiology and pathomechanisms in frontotemporal lobar degeneration
por: Bodea, Liviu‐Gabriel, et al.
Publicado: (2016)

Frontotemporal dementia-associated N279K tau mutant disrupts subcellular vesicle trafficking and induces cellular stress in iPSC-derived neural stem cells
por: Wren, Melissa C., et al.
Publicado: (2015)

Spread of tau down neural circuits precedes synapse and neuronal loss in the rTgTauEC mouse model of early Alzheimer's disease
por: Pickett, Eleanor K., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_4a4t6igl5nfg3308s7nrprq60f