Inhibition of Non-Homologous End Joining Repair Impairs Pancreatic Cancer Growth and Enhances Radiation Response

Pancreatic ductal adenocarcinoma (PDAC) is amongst the deadliest of human cancers, due to its late diagnosis as well as its intense resistance to currently available therapeutics. To identify mechanisms as to why PDAC are refractory to DNA damaging cytoxic chemotherapy and radiation, we performed a...

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Detalles Bibliográficos
Autores principales: Li, Ying-Hua, Wang, Xiaoxu, Pan, Yunfeng, Lee, Dong-Hyun, Chowdhury, Dipanjan, Kimmelman, Alec C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377637/
https://www.ncbi.nlm.nih.gov/pubmed/22724027
http://dx.doi.org/10.1371/journal.pone.0039588

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377637/
https://www.ncbi.nlm.nih.gov/pubmed/22724027
http://dx.doi.org/10.1371/journal.pone.0039588

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