Cargando…

Differential Proteomic Analysis of Human Erythroblasts Undergoing Apoptosis Induced by Epo-Withdrawal

The availability of Erythropoietin (Epo) is essential for the survival of erythroid progenitors. Here we study the effects of Epo removal on primary human erythroblasts grown from peripheral blood CD34(+) cells. The erythroblasts died rapidly from apoptosis, even in the presence of SCF, and within 2...

Descripción completa

Detalles Bibliográficos
Autores principales: Pellegrin, Stéphanie, Heesom, Kate J., Satchwell, Timothy J., Hawley, Bethan R., Daniels, Geoff, van den Akker, Emile, Toye, Ashley M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377639/
https://www.ncbi.nlm.nih.gov/pubmed/22723854
http://dx.doi.org/10.1371/journal.pone.0038356