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Differential Proteomic Analysis of Human Erythroblasts Undergoing Apoptosis Induced by Epo-Withdrawal
The availability of Erythropoietin (Epo) is essential for the survival of erythroid progenitors. Here we study the effects of Epo removal on primary human erythroblasts grown from peripheral blood CD34(+) cells. The erythroblasts died rapidly from apoptosis, even in the presence of SCF, and within 2...
Autores principales: | Pellegrin, Stéphanie, Heesom, Kate J., Satchwell, Timothy J., Hawley, Bethan R., Daniels, Geoff, van den Akker, Emile, Toye, Ashley M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377639/ https://www.ncbi.nlm.nih.gov/pubmed/22723854 http://dx.doi.org/10.1371/journal.pone.0038356 |
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