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Isoflurane Induces Endothelial Apoptosis of the Post-Hypoxic Blood-Brain Barrier in a Transdifferentiated Human Umbilical Vein Edothelial Cell Model

Isoflurane is a popular volatile anesthetic agent used in humans as well as in experimental animal research. In previous animal studies of the blood-brain barrier (BBB), observations towards an increased permeability after exposure to isoflurane are reported. In this study we investigated the effect...

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Detalles Bibliográficos
Autores principales: Dittmar, Michael S., Petermichl, Walter, Schlachetzki, Felix, Graf, Bernhard M., Gruber, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377664/
https://www.ncbi.nlm.nih.gov/pubmed/22723852
http://dx.doi.org/10.1371/journal.pone.0038260