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Isoflurane Induces Endothelial Apoptosis of the Post-Hypoxic Blood-Brain Barrier in a Transdifferentiated Human Umbilical Vein Edothelial Cell Model
Isoflurane is a popular volatile anesthetic agent used in humans as well as in experimental animal research. In previous animal studies of the blood-brain barrier (BBB), observations towards an increased permeability after exposure to isoflurane are reported. In this study we investigated the effect...
Autores principales: | Dittmar, Michael S., Petermichl, Walter, Schlachetzki, Felix, Graf, Bernhard M., Gruber, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377664/ https://www.ncbi.nlm.nih.gov/pubmed/22723852 http://dx.doi.org/10.1371/journal.pone.0038260 |
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