Detection of Crosslinks within and between Proteins by LC-MALDI-TOFTOF and the Software FINDX to Reduce the MSMS-Data to Acquire for Validation

Lysine-specific chemical crosslinking in combination with mass spectrometry is emerging as a tool for the structural characterization of protein complexes and protein-protein interactions. After tryptic digestion of crosslinked proteins there are thousands of peptides amenable to MSMS, of which only...

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Detalles Bibliográficos
Autores principales: Söderberg, Christopher A. G., Lambert, Wietske, Kjellström, Sven, Wiegandt, Alena, Wulff, Ragna Peterson, Månsson, Cecilia, Rutsdottir, Gudrun, Emanuelsson, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377668/
https://www.ncbi.nlm.nih.gov/pubmed/22723907
http://dx.doi.org/10.1371/journal.pone.0038927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377668/
https://www.ncbi.nlm.nih.gov/pubmed/22723907
http://dx.doi.org/10.1371/journal.pone.0038927

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