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Quantification of Alternative Splicing Variants of Human Telomerase Reverse Transcriptase and Correlations with Telomerase Activity in Lung Cancer

Telomerase plays important roles in the development and progression of malignant tumors, and its activity is primarily determined by transcriptional regulation of human telomerase reverse transcriptase (hTERT). Several mRNA alternative splicing variants (ASVs) for hTERT have been identified, but it...

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Detalles Bibliográficos
Autores principales: Liu, Yan, Wu, Bing-quan, Zhong, Hao-hao, Tian, Xin-xia, Fang, Wei-gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377688/
https://www.ncbi.nlm.nih.gov/pubmed/22723897
http://dx.doi.org/10.1371/journal.pone.0038868