Mitochondrial DNA Copy Number, but Not Haplogroup, Confers a Genetic Susceptibility to Leprosy in Han Chinese from Southwest China

BACKGROUND: Leprosy is a chronic infectious disease caused by Mycobacterium leprae, an unculturable pathogen with an exceptionally eroded genome. The high level of inactivation of gene function in M. leprae, including many genes in its metabolic pathways, has led to a dependence on host energy produ...

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Detalles Bibliográficos
Autores principales: Wang, Dong, Su, Ling-Yan, Zhang, A-Mei, Li, Yu-Ye, Li, Xiao-An, Chen, Ling-Ling, Long, Heng, Yao, Yong-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377694/
https://www.ncbi.nlm.nih.gov/pubmed/22719964
http://dx.doi.org/10.1371/journal.pone.0038848

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377694/
https://www.ncbi.nlm.nih.gov/pubmed/22719964
http://dx.doi.org/10.1371/journal.pone.0038848

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