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Minor Protease Inhibitor Mutations at Baseline Do Not Increase the Risk for a Virological Failure in HIV-1 Subtype B Infected Patients

BACKGROUND: Minor protease inhibitor (PI) mutations often exist as polymorphisms in HIV-1 sequences from treatment-naïve patients. Previous studies showed that their presence impairs the antiretroviral treatment (ART) response. Evaluating these findings in a larger cohort is essential. METHODS: To s...

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Detalles Bibliográficos
Autores principales: Scherrer, Alexandra U., Ledergerber, Bruno, von Wyl, Viktor, Böni, Jürg, Yerly, Sabine, Klimkait, Thomas, Cellerai, Cristina, Furrer, Hansjakob, Calmy, Alexandra, Cavassini, Matthias, Elzi, Luigia, Vernazza, Pietro L., Bernasconi, Enos, Günthard, Huldrych F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377720/
https://www.ncbi.nlm.nih.gov/pubmed/22719859
http://dx.doi.org/10.1371/journal.pone.0037983