Activation of Pregnane X Receptor by Pregnenolone 16 α-carbonitrile Prevents High-Fat Diet-Induced Obesity in AKR/J Mice

Pregnane X receptor (PXR) is known to function as a xenobiotic sensor to regulate xenobiotic metabolism through selective transcription of genes responsible for maintaining physiological homeostasis. Here we report that the activation of PXR by pregnenolone 16α-carbonitrile (PCN) in AKR/J mice can p...

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Detalles Bibliográficos
Autores principales: Ma, Yongjie, Liu, Dexi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377726/
https://www.ncbi.nlm.nih.gov/pubmed/22723881
http://dx.doi.org/10.1371/journal.pone.0038734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377726/
https://www.ncbi.nlm.nih.gov/pubmed/22723881
http://dx.doi.org/10.1371/journal.pone.0038734

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