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Segment-Wise Genome-Wide Association Analysis Identifies a Candidate Region Associated with Schizophrenia in Three Independent Samples

Recent studies suggest that variation in complex disorders (e.g., schizophrenia) is explained by a large number of genetic variants with small effect size (Odds Ratio∼1.05–1.1). The statistical power to detect these genetic variants in Genome Wide Association (GWA) studies with large numbers of case...

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Detalles Bibliográficos
Autores principales: Gladwin, Thomas E., Derks, Eske M., Rietschel, Marcella, Mattheisen, Manuel, Breuer, René, Schulze, Thomas G., Nöthen, Markus M., Levinson, Douglas, Shi, Jianxin, Gejman, Pablo V., Cichon, Sven, Ophoff, Roel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377732/
https://www.ncbi.nlm.nih.gov/pubmed/22723893
http://dx.doi.org/10.1371/journal.pone.0038828