Untargeted Plasma Metabolite Profiling Reveals the Broad Systemic Consequences of Xanthine Oxidoreductase Inactivation in Mice

A major challenge in systems biology is integration of molecular findings for individual enzyme activities into a cohesive high-level understanding of cellular metabolism and physiology/pathophysiology. However, meaningful prediction for how a perturbed enzyme activity will globally impact metabolis...

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Detalles Bibliográficos
Autores principales: Chen, Qiuying, Park, Hyeong-Cheon, Goligorsky, Michael S., Chander, Praveen, Fischer, Steven M., Gross, Steven S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377762/
https://www.ncbi.nlm.nih.gov/pubmed/22723833
http://dx.doi.org/10.1371/journal.pone.0037149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377762/
https://www.ncbi.nlm.nih.gov/pubmed/22723833
http://dx.doi.org/10.1371/journal.pone.0037149

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