Disease-drug pairs revealed by computational genomic connectivity mapping on GBA1 deficient, Gaucher disease mice

We have reported that, in addition to recapitulating the classical human Gaucher disease (GD1) phenotype, deletion of the glucocerebrosidase (GBA1) gene in mice results in the dysfunction of a diverse population of immune cells. Most of immune-related, non-classical features of GD1, including gammop...

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Detalles Bibliográficos
Autores principales: Yuen, Tony, Iqbal, Jameel, Zhu, Ling-Ling, Sun, Li, Lin, Aiping, Zhao, Hongyu, Liu, Jun, Mistry, Pramod K., Zaidi, Mone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377787/
https://www.ncbi.nlm.nih.gov/pubmed/22588172
http://dx.doi.org/10.1016/j.bbrc.2012.05.027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377787/
https://www.ncbi.nlm.nih.gov/pubmed/22588172
http://dx.doi.org/10.1016/j.bbrc.2012.05.027

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