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Neurobehavioral phenotyping of G(αq) knockout mice reveals impairments in motor functions and spatial working memory without changes in anxiety or behavioral despair

Many neurotransmitters, hormones, and sensory stimuli elicit their cellular responses through the targeted activation of receptors coupled to the G(αq) family of heterotrimeric G proteins. Nevertheless, we still understand little about the consequences of loss of this signaling activity on brain fun...

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Detalles Bibliográficos
Autores principales: Frederick, Aliya L., Saborido, Tommy P., Stanwood, Gregg D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377978/
https://www.ncbi.nlm.nih.gov/pubmed/22723772
http://dx.doi.org/10.3389/fnbeh.2012.00029