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Prediction and identification of sequences coding for orphan enzymes using genomic and metagenomic neighbours
Despite the current wealth of sequencing data, one-third of all biochemically characterized metabolic enzymes lack a corresponding gene or protein sequence, and as such can be considered orphan enzymes. They represent a major gap between our molecular and biochemical knowledge, and consequently are...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Molecular Biology Organization
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377989/ https://www.ncbi.nlm.nih.gov/pubmed/22569339 http://dx.doi.org/10.1038/msb.2012.13 |