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Mitochondrial DNA That Escapes from Autophagy Causes Inflammation and Heart Failure

Heart failure is a leading cause of morbidity and mortality in industrialized countries. Although infection with microorganisms is not involved in the development of heart failure in most cases, inflammation has been implicated in the pathogenesis of heart failure(1). However, the mechanisms respons...

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Detalles Bibliográficos
Autores principales: Oka, Takafumi, Hikoso, Shungo, Yamaguchi, Osamu, Taneike, Manabu, Takeda, Toshihiro, Tamai, Takahito, Oyabu, Jota, Murakawa, Tomokazu, Nakayama, Hiroyuki, Nishida, Kazuhiko, Akira, Shizuo, Yamamoto, Akitsugu, Komuro, Issei, Otsu, Kinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378041/
https://www.ncbi.nlm.nih.gov/pubmed/22535248
http://dx.doi.org/10.1038/nature10992