Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch critical for myocardial adaptation to ischemia

Studies of metabolic adaptation during environmental stress have broad applications to human disease. Adenosine signaling has been implicated in cardiac adaptation to limited oxygen availability. Serendipitously, a wide search for adenosine receptor A2b (Adora2b)-elicited cardio-adaptive responses i...

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Detalles Bibliográficos
Autores principales: Eckle, Tobias, Hartmann, Katherine, Bonney, Stephanie, Reithel, Susan, Mittelbronn, Michel, Walker, Lori A., Lowes, Brian D., Han, Jun, Borchers, Christoph H., Buttrick, Peter M., Kominsky, Douglas J., Colgan, Sean P., Eltzschig, Holger K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378044/
https://www.ncbi.nlm.nih.gov/pubmed/22504483
http://dx.doi.org/10.1038/nm.2728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378044/
https://www.ncbi.nlm.nih.gov/pubmed/22504483
http://dx.doi.org/10.1038/nm.2728

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